Selank 5mg

Selank 5mg is a synthetic heptapeptide compound designed for research and laboratory use. This high-purity formulation delivers 5 milligrams of Selank, a synthetic analogue of the endogenous immunomodulatory tetrapeptide tuftsin, suitable for scientific investigation and experimental applications exploring cognitive function, mood regulation, and immune response modulation. Each vial is manufactured to exacting standards to ensure consistency and reliability in research settings. Ideal for qualified researchers and institutions studying peptide interactions with neurotransmitter systems, anxiolytic pathways, and immunological responses. Store in a cool, dry place away from direct light. For research purposes only.

Specifications: Active Ingredient: Selank (synthetic tuftsin-derived heptapeptide) Concentration: 5mg per vial Purity: Research-grade Format: Lyophilized powder Storage: Cool, dry environment, 2–8°C (refrigerated) Shelf Life: Refer to batch documentation for expiration details Intended Use: Laboratory and research applications only Quality Standard: Manufactured to pharmaceutical-grade consistency protocols Suitable for qualified researchers, academic institutions, and licensed laboratories conducting cognitive, immunological, and neuropeptide research.

Molecular Formula: C₃₄H₆₁N₁₅O₁₂ Molecular Weight: 821.97 g/mol CAS Number: 61352-05-6 Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro Sequence Classification: Synthetic linear heptapeptide derived from the C-terminal tetrapeptide sequence of tuftsin (Thr-Lys-Pro-Arg) with a Pro-Gly-Pro extension for enhanced stability and CNS penetration Mechanism: Modulates GABA-A receptor activity and influences BDNF expression, serotonin, and dopamine neurotransmitter systems; studied for anxiolytic, nootropic, and immunomodulatory properties without sedative effects Purity Analysis: ≥95% by HPLC This molecular data supports advanced research into neuropeptide pharmacology, anxiety pathway modulation, and immune system regulation studies.

Storage Before Reconstitution: Store the sealed vial at 2–8°C (refrigerated) or at room temperature (15–25°C) in a cool, dry place away from direct sunlight and heat sources. Keep in original packaging to protect from light exposure. Unopened vials maintain stability for the duration specified in batch documentation when stored under these conditions. Storage After Reconstitution: Once reconstituted with bacteriostatic water or sterile saline, store the solution at 2–8°C (refrigerated). Reconstituted solution should be used within the timeframe indicated in your batch documentation. Avoid repeated freeze-thaw cycles, which may compromise peptide integrity. Keep the vial upright and away from direct light during storage. General Handling: Maintain sterile technique during reconstitution. Do not expose to extreme temperatures or prolonged room temperature conditions after mixing. For research use only. Not intended for human or veterinary use.

Research References

The following peer-reviewed studies and publications are provided for informational and scientific reference purposes only. They do not constitute medical claims or endorsements of this product for any therapeutic use.

1. Selank: Design, Synthesis, and Anxiolytic Profile
   Semenova TP, et al. (2010). Selank and short peptides of the tuftsin family in the regulation of adaptive behaviour in rats under conditions of emotional stress. Peptides, 31(5), 921–926. https://doi.org/10.1016/j.peptides.2010.02.006
   Characterises Selank’s anxiolytic and anti-stress activity in rodent models of emotional stress, demonstrating dose-dependent attenuation of anxiety-related behaviour without sedation — establishing the foundational pharmacological profile for Selank research in anxiety pathway modulation and stress neurobiology.
2. Selank and BDNF Expression in the Rat Brain
   Inozemtseva LS, et al. (2008). Intranasal administration of the peptide Selank regulates BDNF expression in the rat hippocampus. Doklady Biological Sciences, 421(1), 241–243. https://doi.org/10.1134/S0012496608040066
   Demonstrates that intranasal Selank administration significantly upregulates BDNF mRNA expression in the rat hippocampus, providing the key neurotrophic mechanism of action for researchers studying Selank in neuroplasticity, memory consolidation, and neuroprotective peptide models.
3. Selank and GABAergic Neurotransmission: Anxiolytic Mechanism
   Zozulya AA, et al. (2001). The influence of Selank on anxiety-related behaviour in rats: interaction with the GABAergic system. Bulletin of Experimental Biology and Medicine, 131(5), 464–466. https://doi.org/10.1023/A:1017928116025
   Demonstrates Selank’s modulation of GABA-A receptor activity and its interaction with benzodiazepine binding sites, establishing the GABAergic mechanism underlying its anxiolytic effects without sedative or amnesic side effects — providing mechanistic context for researchers studying peptide-based anxiolytic compounds.
4. Selank and Immunomodulatory Activity: Tuftsin-Derived Effects
   Uchakina ON, et al. (2008). Immunomodulatory effects of Selank in patients with anxiety-asthenic disorders. Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova, 108(5), 71–75. PMID: 18577961
   Clinical investigation of Selank’s immunomodulatory effects in patients with anxiety disorders, demonstrating normalisation of cytokine profiles (IL-6, TNF-α) and T-cell activity — providing translational evidence for Selank’s dual neuropeptide and immunoregulatory research applications derived from its tuftsin structural origin.
5. Selank and Enkephalin Metabolism: Opioid System Interaction
   Kost NV, et al. (2001). Selank inhibits enkephalin-degrading enzymes in human serum. Bulletin of Experimental Biology and Medicine, 131(4), 362–364. https://doi.org/10.1023/A:1017945809338
   Demonstrates that Selank inhibits enkephalin-degrading enzymes in human serum, prolonging endogenous opioid peptide activity and providing a novel mechanistic pathway for its anxiolytic and mood-modulating effects — expanding the research framework for Selank into endogenous opioid system regulation and neuropeptide stability studies.

All references are cited for scientific context only. This product is supplied strictly for in vitro laboratory research. It is not approved for human or veterinary use.