KLOW 80mg

KLOW 80mg is a synthetic multi-peptide blend designed for research and laboratory use. This high-purity formulation combines four research-grade peptide compounds — GHK-Cu, BPC-157, TB-500, and KPV — into a single 80mg vial, suitable for scientific investigation and experimental applications exploring tissue repair, inflammation modulation, and skin biology. Each vial is manufactured to exacting standards to ensure consistency and reliability in research settings. Ideal for qualified researchers and institutions studying multi-target peptide interactions and regenerative pathways. Store in a cool, dry place away from direct light. For research purposes only.

Specifications: Active Ingredients: GHK-Cu (50mg), BPC-157 (10mg), TB-500 (10mg), KPV (10mg) Total Concentration: 80mg per vial Purity: Research-grade Format: Lyophilized powder Storage: Cool, dry environment, 2–8°C (refrigerated) Shelf Life: Refer to batch documentation for expiration details Intended Use: Laboratory and research applications only Quality Standard: Manufactured to pharmaceutical-grade consistency protocols Suitable for qualified researchers, academic institutions, and licensed laboratories conducting peptide and regenerative biology research.

Molecular Components: GHK-Cu (Copper peptide, 50mg) — Molecular Formula: C₁₄H₂₄CuN₆O₄, Molecular Weight: 403.92 g/mol. A naturally occurring tripeptide-copper complex studied for its role in collagen synthesis, wound healing, and skin vitality. BPC-157 (Body Protection Compound, 10mg) — Molecular Formula: C₂₂H₃₂N₆O₅, Molecular Weight: 1419.55 g/mol. A 15-amino acid partial sequence of body protection compound studied for its role in tissue healing, gut integrity, and cytoprotection. TB-500 (Thymosin Beta-4 fragment, 10mg) — Molecular Formula: C₂₉₇H₄₁₆N₁₁₈O₈₅S, Molecular Weight: 4963.44 g/mol. A synthetic analogue of the actin-sequestering protein thymosin beta-4, studied for its role in cellular migration, angiogenesis, and vascular repair. KPV (Lys-Pro-Val, 10mg) — Molecular Formula: C₁₆H₃₁N₃O₄, Molecular Weight: 311.40 g/mol. A tripeptide derived from the C-terminal sequence of alpha-MSH, studied for its anti-inflammatory and immune-modulatory properties. Purity Analysis: ≥98% by HPLC for each component.

Storage Before Reconstitution: Store the sealed vial at 2–8°C (refrigerated) or at room temperature (15–25°C) in a cool, dry place away from direct sunlight and heat sources. Keep in original packaging to protect from light exposure. Unopened vials maintain stability for the duration specified in batch documentation when stored under these conditions. Storage After Reconstitution: Once reconstituted with bacteriostatic water or appropriate diluent, store the solution at 2–8°C (refrigerated). Reconstituted solution should be used within the timeframe indicated in your batch documentation. Avoid repeated freeze-thaw cycles, which may compromise peptide integrity. Keep the vial upright and away from direct light during storage. General Handling: Maintain sterile technique during reconstitution. Do not expose to extreme temperatures or prolonged room temperature conditions after mixing. For research use only. Not intended for human or veterinary use.

Research References

The following peer-reviewed studies and publications are provided for informational and scientific reference purposes only. They do not constitute medical claims or endorsements of this product for any therapeutic use. References are organised by active component.

GHK-Cu (Copper Tripeptide)

1. GHK-Cu and Collagen Synthesis in Skin Biology
   Pickart L & Margolina A. (2018). Regenerative and protective actions of the GHK-Cu peptide in the light of the new gene data. International Journal of Molecular Sciences, 19(7), 1987. https://doi.org/10.3390/ijms19071987
   Comprehensive review of GHK-Cu’s gene-regulatory activity, demonstrating upregulation of collagen, elastin, and wound-healing genes alongside downregulation of inflammatory and cancer-related pathways — establishing GHK-Cu as a broad-spectrum tissue remodelling research tool.
2. GHK-Cu and Wound Healing in Animal Models
   Pickart L, Vasquez-Soltero JM & Margolina A. (2015). GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration. BioMed Research International, 2015, 648108. https://doi.org/10.1155/2015/648108
   Reviews GHK-Cu’s role in stimulating wound contraction, angiogenesis, and nerve outgrowth in preclinical models, providing mechanistic context for skin repair and regenerative biology research applications.

BPC-157 (Body Protection Compound)

1. BPC-157 and Tendon-to-Bone Healing
   Staresinic M, et al. (2003). Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth. Journal of Orthopaedic Research, 21(6), 976–983. https://doi.org/10.1016/S0736-0266(03)00110-4
   Demonstrates accelerated Achilles tendon healing and in vitro tendocyte proliferation following BPC-157 administration in rat models, establishing its cytoprotective and tissue-repair profile relevant to musculoskeletal research.
2. BPC-157 Cytoprotection and Gut Integrity
   Sikiric P, et al. (2018). Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract. Current Pharmaceutical Design, 24(18), 1990–2001. https://doi.org/10.2174/1381612824666180608101119
   Reviews BPC-157’s cytoprotective mechanisms across gastrointestinal, vascular, and musculoskeletal tissue models, covering NO-system modulation, growth factor upregulation, and anti-inflammatory signalling pathways.

TB-500 (Thymosin Beta-4 Fragment)

1. Thymosin Beta-4 and Actin Sequestration in Tissue Repair
   Goldstein AL, Hannappel E & Kleinman HK. (2005). Thymosin β4: actin-sequestering protein moonlights to repair injured tissues. Trends in Molecular Medicine, 11(9), 421–429. https://doi.org/10.1016/j.molmed.2005.07.004
   Establishes thymosin beta-4’s dual role as an actin-sequestering protein and a pleiotropic tissue repair mediator, covering its promotion of cell migration, angiogenesis, and anti-apoptotic signalling — the mechanistic foundation for TB-500 research.
2. TB-500 and Cardiac Repair in Preclinical Models
   Bock-Marquette I, et al. (2004). Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair. Nature, 432(7016), 466–472. https://doi.org/10.1038/nature03000
   Demonstrates that thymosin beta-4 activates integrin-linked kinase (ILK), promoting cardiomyocyte survival and migration following ischaemic injury in mouse models — a landmark study for TB-500 research in vascular and cardiac repair contexts.

KPV (Lys-Pro-Val)

1. KPV Anti-Inflammatory Activity and α-MSH Derivation
   Catania A, et al. (2004). The neuropeptide alpha-melanocyte-stimulating hormone in the control of inflammation. Pharmacological Reviews, 56(4), 569–611. https://doi.org/10.1124/pr.56.4.3
   Comprehensive review of α-MSH and its C-terminal tripeptide KPV as potent anti-inflammatory mediators, detailing MC1R and MC3R receptor interactions, NF-κB inhibition, and cytokine suppression — establishing the mechanistic basis for KPV’s immune-modulatory research applications.

All references are cited for scientific context only. This product is supplied strictly for in vitro laboratory research. It is not approved for human or veterinary use.