{"product_id":"ghrp-6-5mg","title":"GHRP-6 5mg","description":"\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1007\/3581\/1927\/files\/GHRP-65mg.png?v=1779536247\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cp\u003eGHRP-6 is a growth hormone releasing peptide designed for research and experimental use. This 5mg formulation supports investigation into growth hormone secretion pathways and metabolic processes. Ideal for qualified researchers and laboratories exploring peptide mechanisms in controlled settings. Each vial contains precisely measured GHRP-6 for consistent experimental protocols.\u003c\/p\u003e\n\u003cp\u003eSpecification Peptide: GHRP-6 (Growth Hormone Releasing Peptide-6) Quantity: 5mg per vial Purity: Research grade Form: Lyophilized powder Intended Use: Laboratory and research applications only Storage: Keep in cool, dry conditions away from direct light Reconstitution: Compatible with sterile bacteriostatic water or saline solution\u003c\/p\u003e\n\u003cp\u003eMolecular Formula: C40H69N15O10 Molecular Weight: 873.07 g\/mol Structure: Hexapeptide Sequence: His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 CAS Number: 87616-84-0 Classification: Research peptide, growth hormone secretagogue\u003c\/p\u003e\n\u003cp\u003eStorage Before Reconstitution Store lyophilized GHRP-6 vials at 2–8°C (refrigerated) or at room temperature (15–25°C) in a cool, dry place away from direct sunlight and moisture. Properly sealed vials maintain stability for extended periods under these conditions. Keep away from heat sources and humidity. Storage After Reconstitution Once reconstituted with sterile bacteriostatic water or saline solution, store the solution at 2–8°C (refrigerated). Reconstituted peptide solutions typically remain stable for 2–4 weeks when stored properly in sterile conditions. Always use sterile technique during reconstitution and storage to prevent contamination. Do not freeze reconstituted solutions unless specifically required for your research protocol.\u003c\/p\u003e\n\u003ch2\u003eResearch References\u003c\/h2\u003e\n\u003cp\u003eThe following peer-reviewed studies and publications are provided for informational and scientific reference purposes only. They do not constitute medical claims or endorsements of this product for any therapeutic use.\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHRP-6: Discovery and GH-Releasing Activity\u003c\/strong\u003e\u003cbr\u003eBowers CY, et al. (1991). \u003cem\u003eOn the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone.\u003c\/em\u003e Endocrinology, 128(4), 2027–2035. \u003ca href=\"https:\/\/doi.org\/10.1210\/endo-128-4-2027\"\u003ehttps:\/\/doi.org\/10.1210\/endo-128-4-2027\u003c\/a\u003e\u003cbr\u003eFoundational study characterising GHRP-6 as a potent synthetic hexapeptide GH secretagogue, demonstrating dose-dependent GH release from pituitary somatotrophs both in vitro and in vivo, and establishing its pharmacological profile as distinct from GHRH.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHRP-6 and the Ghrelin Receptor (GHS-R1a)\u003c\/strong\u003e\u003cbr\u003eHoward AD, et al. (1996). \u003cem\u003eA receptor in pituitary and hypothalamus that functions in growth hormone release.\u003c\/em\u003e Science, 273(5277), 974–977. \u003ca href=\"https:\/\/doi.org\/10.1126\/science.273.5277.974\"\u003ehttps:\/\/doi.org\/10.1126\/science.273.5277.974\u003c\/a\u003e\u003cbr\u003eReports the cloning and characterisation of the growth hormone secretagogue receptor (GHS-R1a) — the primary molecular target of GHRP-6 — establishing the receptor biology underpinning all GHRP research and its relationship to the endogenous ghrelin system.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHRP-6 Synergy with GHRH in GH Secretion\u003c\/strong\u003e\u003cbr\u003ePandya N, et al. (1998). \u003cem\u003eGrowth hormone (GH)-releasing peptide-6 requires endogenous hypothalamic GH-releasing hormone for maximal GH stimulation.\u003c\/em\u003e Journal of Clinical Endocrinology \u0026amp; Metabolism, 83(4), 1186–1189. \u003ca href=\"https:\/\/doi.org\/10.1210\/jcem.83.4.4716\"\u003ehttps:\/\/doi.org\/10.1210\/jcem.83.4.4716\u003c\/a\u003e\u003cbr\u003eDemonstrates that GHRP-6’s maximal GH-releasing effect requires intact endogenous GHRH signalling, establishing the synergistic relationship between GHS-R1a agonism and GHRH receptor activation — key context for combination peptide research protocols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHRP-6 and Ghrelin: Appetite and Metabolic Regulation\u003c\/strong\u003e\u003cbr\u003eKojima M, et al. (1999). \u003cem\u003eGhrelin is a growth-hormone-releasing acylated peptide from stomach.\u003c\/em\u003e Nature, 402(6762), 656–660. \u003ca href=\"https:\/\/doi.org\/10.1038\/45230\"\u003ehttps:\/\/doi.org\/10.1038\/45230\u003c\/a\u003e\u003cbr\u003eThe landmark paper identifying ghrelin as the endogenous ligand for GHS-R1a — the same receptor activated by GHRP-6 — establishing the mechanistic link between GHRP-6 activity, appetite stimulation, and metabolic regulation that underpins its orexigenic effects in research models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHRP-6 Cardioprotective Effects in Ischaemia Models\u003c\/strong\u003e\u003cbr\u003eGranado M, et al. (2006). \u003cem\u003eGhrelin and growth hormone secretagogues protect cardiomyocytes from ischemia-reperfusion injury.\u003c\/em\u003e Endocrinology, 147(9), 4484–4492. \u003ca href=\"https:\/\/doi.org\/10.1210\/en.2006-0291\"\u003ehttps:\/\/doi.org\/10.1210\/en.2006-0291\u003c\/a\u003e\u003cbr\u003eDemonstrates that GHRP-6 and related GHS-R1a agonists exert direct cardioprotective effects in rat cardiomyocyte ischaemia-reperfusion models, independent of GH release, via anti-apoptotic and anti-inflammatory signalling — expanding the research scope of GHRP-6 beyond the GH axis.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003eAll references are cited for scientific context only. This product is supplied strictly for in vitro laboratory research. It is not approved for human or veterinary use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mutant Peptides","offers":[{"title":"Default Title","offer_id":53248667287895,"sku":"G65","price":13.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1007\/3581\/1927\/files\/GHRP-65mg.png?v=1779536247","url":"https:\/\/www.mutantpeptides.com\/products\/ghrp-6-5mg","provider":"Mutant Peptides Ltd","version":"1.0","type":"link"}