{"product_id":"ghk-cu-100mg","title":"GHK-CU 100mg","description":"\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1007\/3581\/1927\/files\/GHK-CU100mgG.png?v=1779544115\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cp\u003eGHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper Complex) 100mg is a synthetic tripeptide-copper chelate designed for research and laboratory use. GHK-Cu is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine that has been extensively investigated for its roles in collagen and glycosaminoglycan synthesis, wound healing, angiogenesis, anti-inflammatory signalling, and gene expression regulation. This high-concentration 100mg vial is suitable for extended research protocols and multi-experiment programmes. Each vial is manufactured to pharmaceutical-grade purity standards to ensure consistency and reliability in research settings. Ideal for qualified researchers and institutions studying skin biology, tissue repair, and copper-dependent signalling pathways. Store at 2–8°C. For research purposes only. Not intended for human or veterinary use.\u003c\/p\u003e\n\u003cp\u003eSpecifications: Active Ingredient: GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper(II) complex) Concentration: 100mg per vial Molecular Formula: C₁₄H₂₀CuN₆O₅ Molecular Weight: 404.84 g\/mol CAS Number: 49557-75-7 IUPAC Name: Copper(II) complex of glycyl-L-histidyl-L-lysine Structural Class: Tripeptide-copper chelate complex Copper Content: ~15.7% by weight (Cu²⁺, square planar coordination) pH Stability Range: 4.0–7.5 Purity: ≥98% (HPLC) Form: Lyophilised powder Appearance: White to off-white crystalline powder Storage: 2–8°C (refrigerated) Shelf Life: 24 months from manufacture date Reconstitution: Sterile water or bacteriostatic saline Intended Use: Laboratory and research applications only\u003c\/p\u003e\n\u003cp\u003eStorage Before Reconstitution: Store in original sealed vial at 2–8°C, away from direct light and moisture. Do not freeze. Stable for 24 months from manufacture date. Storage After Reconstitution: Store reconstituted solution at 2–8°C in a sterile container. Stable for up to 30 days refrigerated; bacteriostatic saline preferred for extended post-reconstitution storage. Avoid repeated freeze-thaw cycles. Use aseptic technique throughout. For research use only. Not intended for human or veterinary use.\u003c\/p\u003e\n\u003ch2\u003eResearch References\u003c\/h2\u003e\n\u003cp\u003eThe following peer-reviewed studies and publications are provided for informational and scientific reference purposes only. They do not constitute medical claims or endorsements of this product for any therapeutic use.\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHK-Cu: Discovery and Biological Activity\u003c\/strong\u003e\u003cbr\u003ePickart L. (1981). \u003cem\u003eThe biological effects of the tripeptide glycyl-L-histidyl-L-lysine.\u003c\/em\u003e Biochemical and Biophysical Research Communications, 100(4), 1585–1591. \u003ca href=\"https:\/\/doi.org\/10.1016\/0006-291X(81)90673-0\"\u003ehttps:\/\/doi.org\/10.1016\/0006-291X(81)90673-0\u003c\/a\u003e\u003cbr\u003eFoundational study by the discoverer of GHK-Cu characterising its biological activity as a naturally occurring copper-binding tripeptide, demonstrating its role in stimulating collagen synthesis and establishing the basis for all subsequent GHK-Cu research in wound healing and tissue repair.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHK-Cu and Collagen Synthesis in Skin Biology\u003c\/strong\u003e\u003cbr\u003ePickart L \u0026amp; Margolina A. (2018). \u003cem\u003eRegenerative and protective actions of the GHK-Cu peptide in the light of the new gene data.\u003c\/em\u003e International Journal of Molecular Sciences, 19(7), 1987. \u003ca href=\"https:\/\/doi.org\/10.3390\/ijms19071987\"\u003ehttps:\/\/doi.org\/10.3390\/ijms19071987\u003c\/a\u003e\u003cbr\u003eComprehensive review of GHK-Cu’s gene-regulatory activity across 4,000+ human genes, demonstrating upregulation of collagen, elastin, and wound-healing pathways alongside downregulation of inflammatory and oncogenic gene networks — establishing GHK-Cu as a broad-spectrum tissue remodelling research tool.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHK-Cu and Wound Healing: Preclinical Models\u003c\/strong\u003e\u003cbr\u003ePickart L, Vasquez-Soltero JM \u0026amp; Margolina A. (2015). \u003cem\u003eGHK peptide as a natural modulator of multiple cellular pathways in skin regeneration.\u003c\/em\u003e BioMed Research International, 2015, 648108. \u003ca href=\"https:\/\/doi.org\/10.1155\/2015\/648108\"\u003ehttps:\/\/doi.org\/10.1155\/2015\/648108\u003c\/a\u003e\u003cbr\u003eReviews GHK-Cu’s role in stimulating wound contraction, angiogenesis, nerve outgrowth, and anti-inflammatory signalling in preclinical models, providing mechanistic context for skin repair and regenerative biology research applications.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHK-Cu and Anti-Inflammatory Signalling\u003c\/strong\u003e\u003cbr\u003eCanapp SO Jr, et al. (2003). \u003cem\u003eThe effect of topical tripeptide-copper complex on healing of ischemic open wounds.\u003c\/em\u003e Veterinary Surgery, 32(6), 515–523. \u003ca href=\"https:\/\/doi.org\/10.1053\/j.vetsu.2003.08.003\"\u003ehttps:\/\/doi.org\/10.1053\/j.vetsu.2003.08.003\u003c\/a\u003e\u003cbr\u003eDemonstrates GHK-Cu’s promotion of wound closure, granulation tissue formation, and angiogenesis in ischaemic wound models, providing quantitative healing data and establishing its anti-inflammatory and pro-regenerative profile in controlled preclinical research.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHK-Cu and Gene Expression: Antioxidant and Neuroprotective Pathways\u003c\/strong\u003e\u003cbr\u003ePickart L, Vasquez-Soltero JM \u0026amp; Margolina A. (2017). \u003cem\u003eThe human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging: implications for cognitive health.\u003c\/em\u003e Oxidative Medicine and Cellular Longevity, 2017, 1546138. \u003ca href=\"https:\/\/doi.org\/10.1155\/2017\/1546138\"\u003ehttps:\/\/doi.org\/10.1155\/2017\/1546138\u003c\/a\u003e\u003cbr\u003eReviews GHK-Cu’s upregulation of antioxidant defence genes (SOD, catalase, glutathione pathways) and neuroprotective gene networks, providing research context for investigators studying GHK-Cu in oxidative stress, neurodegeneration, and age-related cellular decline models.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003eAll references are cited for scientific context only. This product is supplied strictly for in vitro laboratory research. It is not approved for human or veterinary use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mutant Peptides","offers":[{"title":"Default Title","offer_id":53248638320983,"sku":"CU100","price":35.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1007\/3581\/1927\/files\/GHK-CU100mgG.png?v=1779544115","url":"https:\/\/www.mutantpeptides.com\/products\/ghk-cu-100mg","provider":"Mutant Peptides Ltd","version":"1.0","type":"link"}