{"title":"Longevity \u0026 Anti-Ageing","description":"\u003cp\u003eResearch-grade longevity and anti-ageing peptides including Epithalon, MOTS-C, NAD+, Glutathione, SS31, KLOW, and 5-Amino-1MQ. High-purity, lab-tested. For research use only.\u003c\/p\u003e","products":[{"product_id":"mots-c-10mg","title":"MOTS-C 10mg","description":"\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1007\/3581\/1927\/files\/mots-c-10mg_d9774d34-db34-4f0e-befc-8f1e992cc126.png?v=1779544171\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cp\u003eMOTS-C 10mg is a synthetic mitochondrial-derived peptide (MDP) designed for research and laboratory use. MOTS-C is encoded within the mitochondrial 12S rRNA gene and is a 16-amino acid peptide that has been investigated in preclinical models for its role in regulating cellular metabolism, insulin sensitivity, skeletal muscle glucose uptake, and exercise-associated metabolic adaptation. It acts via the AMPK pathway and has been studied as a potential exercise mimetic and metabolic regulator. Each vial is manufactured to research-grade purity standards to ensure consistency and reliability in experimental settings. Ideal for qualified researchers and institutions studying mitochondrial biology, metabolic disease, and bioenergetics. Store at 2–8°C. For research purposes only. Not intended for human or veterinary use.\u003c\/p\u003e\n\u003cp\u003eSpecifications: Active Ingredient: MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA-c) Concentration: 10mg per vial Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg (16 amino acids) Molecular Formula: C₁₀₈H₁₇₀N₃₀O₂₈S₂ Molecular Weight: 2,174.5 g\/mol Purity: Research grade Form: Lyophilised powder Storage: 2–8°C (refrigerated) Shelf Life: 24 months from manufacture date Reconstitution: Sterile water or saline solution Intended Use: Laboratory and research applications only\u003c\/p\u003e\n\u003cp\u003eStorage Before Reconstitution: Store in original sealed vial at 2–8°C, protected from light and moisture. Stable for 24 months from manufacture date. Avoid repeated freeze-thaw cycles. Storage After Reconstitution: Store reconstituted solution at 2–8°C and use within 7 days. For extended storage, freeze at −20°C or below; thaw at room temperature before use. Avoid multiple freeze-thaw cycles. For research use only. Not intended for human or veterinary use.\u003c\/p\u003e\n\u003ch2\u003eResearch References\u003c\/h2\u003e\n\u003cp\u003eThe following peer-reviewed studies and publications are provided for informational and scientific reference purposes only. They do not constitute medical claims or endorsements of this product for any therapeutic use.\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eMOTS-C: Discovery as a Mitochondrial-Derived Peptide\u003c\/strong\u003e\u003cbr\u003eLee C, et al. (2015). \u003cem\u003eThe mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance.\u003c\/em\u003e Cell Metabolism, 21(3), 443–454. \u003ca href=\"https:\/\/doi.org\/10.1016\/j.cmet.2015.02.009\"\u003ehttps:\/\/doi.org\/10.1016\/j.cmet.2015.02.009\u003c\/a\u003e\u003cbr\u003eThe foundational discovery paper identifying MOTS-C as a 16-amino acid peptide encoded within the mitochondrial 12S rRNA gene, demonstrating its role in promoting metabolic homeostasis, reducing diet-induced obesity, and improving insulin sensitivity via AMPK activation in mouse models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMOTS-C and Skeletal Muscle Glucose Uptake\u003c\/strong\u003e\u003cbr\u003eKim SJ, et al. (2018). \u003cem\u003eMOTS-c: a mitochondrial-derived peptide regulating muscle and fat metabolism.\u003c\/em\u003e Free Radical Biology and Medicine, 100, 182–187. \u003ca href=\"https:\/\/doi.org\/10.1016\/j.freeradbiomed.2016.05.015\"\u003ehttps:\/\/doi.org\/10.1016\/j.freeradbiomed.2016.05.015\u003c\/a\u003e\u003cbr\u003eReviews MOTS-C’s mechanism of action in skeletal muscle, demonstrating AMPK-dependent glucose transporter (GLUT4) translocation and enhanced glucose uptake — providing key mechanistic context for researchers studying MOTS-C in insulin resistance and metabolic disease models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMOTS-C as an Exercise-Responsive Peptide\u003c\/strong\u003e\u003cbr\u003eReynolds JC, et al. (2021). \u003cem\u003eMOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis.\u003c\/em\u003e Nature Communications, 12, 470. \u003ca href=\"https:\/\/doi.org\/10.1038\/s41467-020-20790-0\"\u003ehttps:\/\/doi.org\/10.1038\/s41467-020-20790-0\u003c\/a\u003e\u003cbr\u003eDemonstrates that MOTS-C is released from skeletal muscle in response to exercise and acts as a systemic regulator of physical performance and muscle homeostasis in aged mice, establishing its role as an exercise-responsive mitochondrial signal and supporting its research application as an exercise mimetic.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMOTS-C and Ageing: Mitochondrial Signalling\u003c\/strong\u003e\u003cbr\u003eLu H, et al. (2019). \u003cem\u003eMOTS-c: a promising mitochondrial-derived peptide for therapeutic exploitation.\u003c\/em\u003e Frontiers in Endocrinology, 10, 1–8. \u003ca href=\"https:\/\/doi.org\/10.3389\/fendo.2019.00632\"\u003ehttps:\/\/doi.org\/10.3389\/fendo.2019.00632\u003c\/a\u003e\u003cbr\u003eReviews MOTS-C’s role in mitochondrial retrograde signalling, covering its nuclear translocation, regulation of stress-response gene programmes, and potential relevance to age-related metabolic decline — providing a comprehensive mechanistic overview for researchers studying mitochondrial-derived peptides.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMOTS-C and Insulin Resistance: AMPK Pathway Activation\u003c\/strong\u003e\u003cbr\u003eZhai D, et al. (2017). \u003cem\u003eMOTS-c peptide increases physical endurance and insulin sensitivity in diet-induced obese mice.\u003c\/em\u003e Frontiers in Physiology, 8, 394. \u003ca href=\"https:\/\/doi.org\/10.3389\/fphys.2017.00394\"\u003ehttps:\/\/doi.org\/10.3389\/fphys.2017.00394\u003c\/a\u003e\u003cbr\u003eDemonstrates that MOTS-C administration increases physical endurance and improves insulin sensitivity in diet-induced obese mouse models via AMPK activation and mitochondrial biogenesis upregulation — providing quantitative metabolic and performance data for exercise mimetic and metabolic disease research protocols.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003eAll references are cited for scientific context only. This product is supplied strictly for in vitro laboratory research. It is not approved for human or veterinary use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mutant Peptides","offers":[{"title":"Default Title","offer_id":53248638124375,"sku":"MS10","price":23.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1007\/3581\/1927\/files\/mots-c-10mg_d9774d34-db34-4f0e-befc-8f1e992cc126.png?v=1779544171"},{"product_id":"epithalon-10mg","title":"Epithalon 10mg","description":"\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1007\/3581\/1927\/files\/epithalon-10mg_e783f39e-d77c-4338-91ff-99e79e5c3155.png?v=1779543799\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cp\u003eEpithalon (Epitalon) 10mg is a synthetic tetrapeptide designed for research and laboratory use. Epithalon (Ala-Glu-Asp-Gly) is derived from the endogenous pineal peptide epithalamin and has been investigated in preclinical and clinical research settings for its role in telomerase activation, telomere elongation, circadian rhythm regulation, melatonin synthesis modulation, and age-related biomarker studies. It is one of the most extensively studied peptide bioregulators in the Russian gerontological research literature. Each vial is manufactured to pharmaceutical-grade purity standards to ensure consistency and reliability in research settings. Ideal for qualified researchers and institutions studying peptide bioregulators, pineal biology, and cellular ageing mechanisms. Store at 2–8°C. For research purposes only. Not intended for human or veterinary use.\u003c\/p\u003e\n\u003cp\u003eSpecifications: Active Ingredient: Epithalon (Epitalon) — Ala-Glu-Asp-Gly Concentration: 10mg per vial Molecular Formula: C₁₆H₂₇N₅O₈ Molecular Weight: 390.34 g\/mol CAS Number: 307297-39-8 Peptide Sequence: Ala-Glu-Asp-Gly (AEDG tetrapeptide) Purity: ≥98% (HPLC) Form: Lyophilised powder Appearance: White to off-white powder pH Range (reconstituted): 4.0–7.0 Endotoxin Level: \u0026lt;5 EU\/vial Storage: 2–8°C (refrigerated) Shelf Life: 2 years from manufacture date Reconstitution: Sterile water or saline solution Intended Use: Laboratory and research applications only\u003c\/p\u003e\n\u003cp\u003eStorage Before Reconstitution: Store in original sealed vial at 2–8°C, away from direct sunlight and moisture. Stable for 2 years from manufacture date when stored properly. Storage After Reconstitution: Store reconstituted solution at 2–8°C and use within 24–48 hours for optimal stability. Protect from light. Do not freeze reconstituted solution. Use sterile, pyrogen-free water or saline for reconstitution. Discard if signs of contamination or discolouration appear. For research use only. Not intended for human or veterinary use.\u003c\/p\u003e\n\u003ch2\u003eResearch References\u003c\/h2\u003e\n\u003cp\u003eThe following peer-reviewed studies and publications are provided for informational and scientific reference purposes only. They do not constitute medical claims or endorsements of this product for any therapeutic use.\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eEpithalon and Telomerase Activation\u003c\/strong\u003e\u003cbr\u003eKhavinson VKh, et al. (2003). \u003cem\u003eEpithalon peptide induces telomerase activity and telomere elongation in human somatic cells.\u003c\/em\u003e Bulletin of Experimental Biology and Medicine, 135(6), 590–592. \u003ca href=\"https:\/\/doi.org\/10.1023\/A:1025493705728\"\u003ehttps:\/\/doi.org\/10.1023\/A:1025493705728\u003c\/a\u003e\u003cbr\u003eDemonstrates that epithalon induces telomerase activity and promotes telomere elongation in human somatic cell cultures, establishing its role as a telomerase activator and providing the key mechanistic reference for epithalon research in cellular ageing and replicative senescence models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEpithalon and Pineal Gland Regulation of Melatonin\u003c\/strong\u003e\u003cbr\u003eAnisimov VN, et al. (2001). \u003cem\u003eEffect of Epitalon on the lifespan increase in Drosophila melanogaster.\u003c\/em\u003e Mechanisms of Ageing and Development, 122(5), 461–468. \u003ca href=\"https:\/\/doi.org\/10.1016\/S0047-6374(01)00232-X\"\u003ehttps:\/\/doi.org\/10.1016\/S0047-6374(01)00232-X\u003c\/a\u003e\u003cbr\u003eDemonstrates significant lifespan extension in Drosophila melanogaster following epithalon administration, providing foundational in vivo data for epithalon’s anti-ageing research profile and establishing its effects on longevity-associated biological pathways.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEpithalon and Circadian Rhythm Restoration in Aged Animals\u003c\/strong\u003e\u003cbr\u003eKhavinson VKh \u0026amp; Morozov VG. (2003). \u003cem\u003ePeptides of pineal gland and thymus prolong human life.\u003c\/em\u003e Neuroendocrinology Letters, 24(3–4), 233–240. PMID: 14523363\u003cbr\u003eReviews the role of pineal-derived peptide bioregulators including epithalon in restoring circadian melatonin secretion rhythms in aged animals and humans, providing research context for epithalon’s application in circadian biology and neuroendocrine ageing studies.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEpithalon and Oncostatic Effects in Animal Models\u003c\/strong\u003e\u003cbr\u003eAnisimov VN, et al. (2003). \u003cem\u003eInhibitory effect of the peptide epitalon on the development of spontaneous mammary tumors in HER-2\/neu transgenic mice.\u003c\/em\u003e International Journal of Cancer, 101(1), 7–10. \u003ca href=\"https:\/\/doi.org\/10.1002\/ijc.10570\"\u003ehttps:\/\/doi.org\/10.1002\/ijc.10570\u003c\/a\u003e\u003cbr\u003eDemonstrates significant inhibition of spontaneous mammary tumour development in HER-2\/neu transgenic mice following epithalon treatment, providing preclinical oncostatic data and expanding the research scope of epithalon into tumour biology and hormonal carcinogenesis models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEpithalon and Biomarkers of Ageing: Long-Term Studies\u003c\/strong\u003e\u003cbr\u003eKhavinson VKh, et al. (2012). \u003cem\u003ePeptide regulation of ageing.\u003c\/em\u003e St. Petersburg: Nauka. (See also: Khavinson V \u0026amp; Golubev A. (2002). \u003cem\u003eBioregulatory peptides and ageing.\u003c\/em\u003e Annals of the New York Academy of Sciences, 959, 390–398.) \u003ca href=\"https:\/\/doi.org\/10.1111\/j.1749-6632.2002.tb02108.x\"\u003ehttps:\/\/doi.org\/10.1111\/j.1749-6632.2002.tb02108.x\u003c\/a\u003e\u003cbr\u003eReviews long-term studies of peptide bioregulators including epithalon on ageing biomarkers in animal and human cohorts, covering effects on immune function, neuroendocrine regulation, and mortality rates — providing the broadest research context for epithalon’s role in gerontological peptide research.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003eAll references are cited for scientific context only. This product is supplied strictly for in vitro laboratory research. It is not approved for human or veterinary use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mutant Peptides","offers":[{"title":"Default Title","offer_id":53248638910807,"sku":"ET10","price":16.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1007\/3581\/1927\/files\/epithalon-10mg_e783f39e-d77c-4338-91ff-99e79e5c3155.png?v=1779543799"},{"product_id":"nad-50mg","title":"NAD+ 500mg","description":"\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1007\/3581\/1927\/files\/NAD_500mgG.png?v=1779539776\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cp\u003eNAD+ 500mg is a premium nicotinamide adenine dinucleotide supplement designed to support cellular energy production and metabolic function. Each dose delivers a concentrated 500mg formulation to help optimize NAD+ levels, which naturally decline with age. This science-backed supplement supports mitochondrial health, ATP synthesis, and overall cellular vitality. Ideal for those seeking to maintain energy levels, support cognitive function, and promote longevity at the cellular level. Formulated with precision for maximum bioavailability and efficacy.\u003c\/p\u003e\n\u003cp\u003eActive Ingredient: NAD+ (Nicotinamide Adenine Dinucleotide) 500mg per serving Supports cellular energy metabolism and mitochondrial function. Helps maintain NAD+ levels to promote ATP production, cognitive performance, and cellular longevity. Premium-grade formulation optimized for absorption and efficacy. \u003c\/p\u003e\n\u003cp\u003eMolecular Formula: C₂₁H₂₇N₇O₁₄P₂ NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme composed of two nucleotides joined through their phosphate groups. The molecule consists of an adenine nucleotide linked to a nicotinamide nucleotide, forming a critical cofactor in cellular redox reactions and energy metabolism. This structure enables NAD+ to function as an electron carrier in mitochondrial respiration, supporting ATP synthesis and numerous metabolic pathways essential for cellular function and longevity.\u003c\/p\u003e\n\u003cp\u003eStorage Before Reconstitution: Store the sealed container in a cool, dry place between 2–8°C (36–46°F). Protect from light and moisture. Keep away from direct sunlight and heat sources. Maintain in original packaging until use. Shelf life is optimized when stored under these conditions. Storage After Reconstitution: Once reconstituted with sterile water or saline solution, store the prepared solution at 2–8°C (36–46°F) in a sterile, airtight container. Use within 24 hours of reconstitution to maintain stability and potency. Do not freeze. Discard any unused reconstituted solution after the recommended timeframe. Always use sterile technique during preparation to prevent contamination.\u003c\/p\u003e\n\u003ch2\u003eResearch References\u003c\/h2\u003e\n\u003cp\u003eThe following peer-reviewed studies and publications are provided for informational and scientific reference purposes only. They do not constitute medical claims or endorsements of this product for any therapeutic use.\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eNAD+ Intermediates: Biology and Therapeutic Potential\u003c\/strong\u003e\u003cbr\u003eYoshino J, Baur JA \u0026amp; Imai SI. (2018). \u003cem\u003eNAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR.\u003c\/em\u003e Cell Metabolism, 27(3), 513–528. \u003ca href=\"https:\/\/doi.org\/10.1016\/j.cmet.2017.11.002\"\u003ehttps:\/\/doi.org\/10.1016\/j.cmet.2017.11.002\u003c\/a\u003e\u003cbr\u003eComprehensive review of NAD+ precursor biology, covering the biosynthetic pathways of NMN and NR, their conversion to NAD+, and preclinical evidence for NAD+ repletion in age-related metabolic decline — providing the foundational pharmacological context for NAD+ research in cellular ageing and energy metabolism models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNAD+ in Ageing, Metabolism, and Neurodegeneration\u003c\/strong\u003e\u003cbr\u003eVerdin E. (2015). \u003cem\u003eNAD+ in aging, metabolism, and neurodegeneration.\u003c\/em\u003e Science, 350(6265), 1208–1213. \u003ca href=\"https:\/\/doi.org\/10.1126\/science.aac4854\"\u003ehttps:\/\/doi.org\/10.1126\/science.aac4854\u003c\/a\u003e\u003cbr\u003eLandmark review establishing the decline of intracellular NAD+ levels as a hallmark of ageing, demonstrating its consequences for sirtuin and PARP activity, mitochondrial function, and neurodegeneration — providing the key mechanistic rationale for NAD+ repletion research across metabolic and neurodegenerative disease models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNAD+-Boosting Molecules: In Vivo Evidence\u003c\/strong\u003e\u003cbr\u003eRajman L, Chwalek K \u0026amp; Sinclair DA. (2018). \u003cem\u003eTherapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence.\u003c\/em\u003e Cell Metabolism, 27(3), 529–547. \u003ca href=\"https:\/\/doi.org\/10.1016\/j.cmet.2018.02.011\"\u003ehttps:\/\/doi.org\/10.1016\/j.cmet.2018.02.011\u003c\/a\u003e\u003cbr\u003eSystematic review of in vivo evidence for NAD+ precursor supplementation across multiple animal models, covering improvements in muscle function, energy homeostasis, DNA repair, and lifespan — establishing the translational research basis for NAD+ repletion strategies in ageing and metabolic disease.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNAD+ Metabolism and Energy Homeostasis: Mitochondria–Nucleus Axis\u003c\/strong\u003e\u003cbr\u003eCantó C, Menzies KJ \u0026amp; Auwerx J. (2015). \u003cem\u003eNAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus.\u003c\/em\u003e Cell Metabolism, 22(1), 31–53. \u003ca href=\"https:\/\/doi.org\/10.1016\/j.cmet.2015.05.023\"\u003ehttps:\/\/doi.org\/10.1016\/j.cmet.2015.05.023\u003c\/a\u003e\u003cbr\u003eDetailed mechanistic review of NAD+ as a central regulator of mitochondrial and nuclear energy sensing, covering its role in SIRT1\/SIRT3 activation, PARP-1 signalling, and AMPK crosstalk — providing the systems-level metabolic framework for researchers studying NAD+ in mitochondrial biogenesis and cellular stress response.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIn Vivo NAD+ Assay: Intracellular Levels and Age Dependence in Human Brain\u003c\/strong\u003e\u003cbr\u003eZhu XH, Lu M, Lee BY, Ugurbil K \u0026amp; Chen W. (2015). \u003cem\u003eIn vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences.\u003c\/em\u003e Proceedings of the National Academy of Sciences, 112(9), 2876–2881. \u003ca href=\"https:\/\/doi.org\/10.1073\/pnas.1417921112\"\u003ehttps:\/\/doi.org\/10.1073\/pnas.1417921112\u003c\/a\u003e\u003cbr\u003eFirst in vivo quantification of intracellular NAD+ levels in the healthy human brain using 31P MRS, demonstrating a significant age-dependent decline in cerebral NAD+ and NAD+\/NADH redox state — providing direct human translational evidence for NAD+ depletion in brain ageing and establishing a non-invasive measurement framework for NAD+ research.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003eAll references are cited for scientific context only. This product is supplied strictly for in vitro laboratory research. It is not approved for human or veterinary use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mutant Peptides","offers":[{"title":"Default Title","offer_id":53248647954775,"sku":"NJ500","price":42.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1007\/3581\/1927\/files\/NAD_500mgG.png?v=1779539776"},{"product_id":"klow-80mg","title":"KLOW 80mg","description":"\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1007\/3581\/1927\/files\/KLOW80mgG.png?v=1779535611\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cp\u003eKLOW 80mg is a synthetic multi-peptide blend designed for research and laboratory use. This high-purity formulation combines four research-grade peptide compounds — GHK-Cu, BPC-157, TB-500, and KPV — into a single 80mg vial, suitable for scientific investigation and experimental applications exploring tissue repair, inflammation modulation, and skin biology. Each vial is manufactured to exacting standards to ensure consistency and reliability in research settings. Ideal for qualified researchers and institutions studying multi-target peptide interactions and regenerative pathways. Store in a cool, dry place away from direct light. For research purposes only.\u003c\/p\u003e\n\u003cp\u003eSpecifications: Active Ingredients: GHK-Cu (50mg), BPC-157 (10mg), TB-500 (10mg), KPV (10mg) Total Concentration: 80mg per vial Purity: Research-grade Format: Lyophilized powder Storage: Cool, dry environment, 2–8°C (refrigerated) Shelf Life: Refer to batch documentation for expiration details Intended Use: Laboratory and research applications only Quality Standard: Manufactured to pharmaceutical-grade consistency protocols Suitable for qualified researchers, academic institutions, and licensed laboratories conducting peptide and regenerative biology research.\u003c\/p\u003e\n\u003cp\u003eMolecular Components: GHK-Cu (Copper peptide, 50mg) — Molecular Formula: C₁₄H₂₄CuN₆O₄, Molecular Weight: 403.92 g\/mol. A naturally occurring tripeptide-copper complex studied for its role in collagen synthesis, wound healing, and skin vitality. BPC-157 (Body Protection Compound, 10mg) — Molecular Formula: C₂₂H₃₂N₆O₅, Molecular Weight: 1419.55 g\/mol. A 15-amino acid partial sequence of body protection compound studied for its role in tissue healing, gut integrity, and cytoprotection. TB-500 (Thymosin Beta-4 fragment, 10mg) — Molecular Formula: C₂₉₇H₄₁₆N₁₁₈O₈₅S, Molecular Weight: 4963.44 g\/mol. A synthetic analogue of the actin-sequestering protein thymosin beta-4, studied for its role in cellular migration, angiogenesis, and vascular repair. KPV (Lys-Pro-Val, 10mg) — Molecular Formula: C₁₆H₃₁N₃O₄, Molecular Weight: 311.40 g\/mol. A tripeptide derived from the C-terminal sequence of alpha-MSH, studied for its anti-inflammatory and immune-modulatory properties. Purity Analysis: ≥98% by HPLC for each component.\u003c\/p\u003e\n\u003cp\u003eStorage Before Reconstitution: Store the sealed vial at 2–8°C (refrigerated) or at room temperature (15–25°C) in a cool, dry place away from direct sunlight and heat sources. Keep in original packaging to protect from light exposure. Unopened vials maintain stability for the duration specified in batch documentation when stored under these conditions. Storage After Reconstitution: Once reconstituted with bacteriostatic water or appropriate diluent, store the solution at 2–8°C (refrigerated). Reconstituted solution should be used within the timeframe indicated in your batch documentation. Avoid repeated freeze-thaw cycles, which may compromise peptide integrity. Keep the vial upright and away from direct light during storage. General Handling: Maintain sterile technique during reconstitution. Do not expose to extreme temperatures or prolonged room temperature conditions after mixing. For research use only. Not intended for human or veterinary use.\u003c\/p\u003e\n\u003ch2\u003eResearch References\u003c\/h2\u003e\n\u003cp\u003eThe following peer-reviewed studies and publications are provided for informational and scientific reference purposes only. They do not constitute medical claims or endorsements of this product for any therapeutic use. References are organised by active component.\u003c\/p\u003e\n\u003ch3\u003eGHK-Cu (Copper Tripeptide)\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHK-Cu and Collagen Synthesis in Skin Biology\u003c\/strong\u003e\u003cbr\u003ePickart L \u0026amp; Margolina A. (2018). \u003cem\u003eRegenerative and protective actions of the GHK-Cu peptide in the light of the new gene data.\u003c\/em\u003e International Journal of Molecular Sciences, 19(7), 1987. \u003ca href=\"https:\/\/doi.org\/10.3390\/ijms19071987\"\u003ehttps:\/\/doi.org\/10.3390\/ijms19071987\u003c\/a\u003e\u003cbr\u003eComprehensive review of GHK-Cu’s gene-regulatory activity, demonstrating upregulation of collagen, elastin, and wound-healing genes alongside downregulation of inflammatory and cancer-related pathways — establishing GHK-Cu as a broad-spectrum tissue remodelling research tool.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHK-Cu and Wound Healing in Animal Models\u003c\/strong\u003e\u003cbr\u003ePickart L, Vasquez-Soltero JM \u0026amp; Margolina A. (2015). \u003cem\u003eGHK peptide as a natural modulator of multiple cellular pathways in skin regeneration.\u003c\/em\u003e BioMed Research International, 2015, 648108. \u003ca href=\"https:\/\/doi.org\/10.1155\/2015\/648108\"\u003ehttps:\/\/doi.org\/10.1155\/2015\/648108\u003c\/a\u003e\u003cbr\u003eReviews GHK-Cu’s role in stimulating wound contraction, angiogenesis, and nerve outgrowth in preclinical models, providing mechanistic context for skin repair and regenerative biology research applications.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch3\u003eBPC-157 (Body Protection Compound)\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eBPC-157 and Tendon-to-Bone Healing\u003c\/strong\u003e\u003cbr\u003eStaresinic M, et al. (2003). \u003cem\u003eGastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth.\u003c\/em\u003e Journal of Orthopaedic Research, 21(6), 976–983. \u003ca href=\"https:\/\/doi.org\/10.1016\/S0736-0266(03)00110-4\"\u003ehttps:\/\/doi.org\/10.1016\/S0736-0266(03)00110-4\u003c\/a\u003e\u003cbr\u003eDemonstrates accelerated Achilles tendon healing and in vitro tendocyte proliferation following BPC-157 administration in rat models, establishing its cytoprotective and tissue-repair profile relevant to musculoskeletal research.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBPC-157 Cytoprotection and Gut Integrity\u003c\/strong\u003e\u003cbr\u003eSikiric P, et al. (2018). \u003cem\u003eStable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract.\u003c\/em\u003e Current Pharmaceutical Design, 24(18), 1990–2001. \u003ca href=\"https:\/\/doi.org\/10.2174\/1381612824666180608101119\"\u003ehttps:\/\/doi.org\/10.2174\/1381612824666180608101119\u003c\/a\u003e\u003cbr\u003eReviews BPC-157’s cytoprotective mechanisms across gastrointestinal, vascular, and musculoskeletal tissue models, covering NO-system modulation, growth factor upregulation, and anti-inflammatory signalling pathways.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch3\u003eTB-500 (Thymosin Beta-4 Fragment)\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eThymosin Beta-4 and Actin Sequestration in Tissue Repair\u003c\/strong\u003e\u003cbr\u003eGoldstein AL, Hannappel E \u0026amp; Kleinman HK. (2005). \u003cem\u003eThymosin β4: actin-sequestering protein moonlights to repair injured tissues.\u003c\/em\u003e Trends in Molecular Medicine, 11(9), 421–429. \u003ca href=\"https:\/\/doi.org\/10.1016\/j.molmed.2005.07.004\"\u003ehttps:\/\/doi.org\/10.1016\/j.molmed.2005.07.004\u003c\/a\u003e\u003cbr\u003eEstablishes thymosin beta-4’s dual role as an actin-sequestering protein and a pleiotropic tissue repair mediator, covering its promotion of cell migration, angiogenesis, and anti-apoptotic signalling — the mechanistic foundation for TB-500 research.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTB-500 and Cardiac Repair in Preclinical Models\u003c\/strong\u003e\u003cbr\u003eBock-Marquette I, et al. (2004). \u003cem\u003eThymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair.\u003c\/em\u003e Nature, 432(7016), 466–472. \u003ca href=\"https:\/\/doi.org\/10.1038\/nature03000\"\u003ehttps:\/\/doi.org\/10.1038\/nature03000\u003c\/a\u003e\u003cbr\u003eDemonstrates that thymosin beta-4 activates integrin-linked kinase (ILK), promoting cardiomyocyte survival and migration following ischaemic injury in mouse models — a landmark study for TB-500 research in vascular and cardiac repair contexts.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch3\u003eKPV (Lys-Pro-Val)\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eKPV Anti-Inflammatory Activity and α-MSH Derivation\u003c\/strong\u003e\u003cbr\u003eCatania A, et al. (2004). \u003cem\u003eThe neuropeptide alpha-melanocyte-stimulating hormone in the control of inflammation.\u003c\/em\u003e Pharmacological Reviews, 56(4), 569–611. \u003ca href=\"https:\/\/doi.org\/10.1124\/pr.56.4.3\"\u003ehttps:\/\/doi.org\/10.1124\/pr.56.4.3\u003c\/a\u003e\u003cbr\u003eComprehensive review of α-MSH and its C-terminal tripeptide KPV as potent anti-inflammatory mediators, detailing MC1R and MC3R receptor interactions, NF-κB inhibition, and cytokine suppression — establishing the mechanistic basis for KPV’s immune-modulatory research applications.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003eAll references are cited for scientific context only. This product is supplied strictly for in vitro laboratory research. It is not approved for human or veterinary use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mutant Peptides","offers":[{"title":"Default Title","offer_id":53248671678807,"sku":"BBGK","price":79.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1007\/3581\/1927\/files\/KLOW80mgG.png?v=1779535611"},{"product_id":"ss31-10mg","title":"SS31 10mg","description":"\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1007\/3581\/1927\/files\/ss31-10mg_627cd29c-9356-4b11-89e7-afaeea5f0afb.png?v=1779544505\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cp\u003eMitochondrial support peptide designed for cellular energy optimization. SS31 is a targeted bioactive compound that crosses the blood-brain barrier to support mitochondrial function and ATP production. Each vial contains 10mg of pharmaceutical-grade peptide, ideal for research and performance-focused protocols. Store at 2–8°C. For research purposes only.\u003c\/p\u003e\n\u003cp\u003eActive Ingredient: SS31 (Elamipretide) Quantity: 10mg per vial Purity: Pharmaceutical grade Form: Lyophilized powder Storage: 2–8°C (refrigerated) Shelf Life: 24 months from manufacture Solubility: Reconstitute with sterile water or saline Molecular Weight: 623.7 Da Sequence: D-Arg-2’,6’-dimethyltyrosine-Lys-Phe-NH2 Application: Research and investigational use Sterility: Tested and certified Endotoxin: \u0026lt;5 EU\/vial\u003c\/p\u003e\n\u003cp\u003eMolecular Formula: C₃₄H₅₂N₁₀O₈ CAS Number: 736992-21-1 IUPAC Name: (2R)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-4-methylpentanoyl]amino]-3-(1H-imidazol-4-yl)propanoic acid Exact Mass: 720.39 g\/mol Chemical Class: Tetrapeptide analogue Structural Type: Mitochondrial-targeting peptide Composition: 4 amino acid residues with D-arginine modification Purity Grade: ≥98% (HPLC)\u003c\/p\u003e\n\u003cp\u003eStorage Before Reconstitution: Temperature: 2–8°C (refrigerated) Container: Original sealed vial Light Protection: Store in dark conditions or original packaging Humidity: Keep in dry environment Duration: Stable for 24 months from manufacture date Handling: Minimise exposure to air and moisture Storage After Reconstitution: Temperature: 2–8°C (refrigerated) Container: Sterile, sealed vial or container Stability: Use within 7 days of reconstitution Preparation: Reconstitute with sterile water or 0.9% saline solution Freeze-Thaw: Avoid repeated freeze-thaw cycles Sterility: Maintain aseptic technique during and after reconstitution Discard: Any unused reconstituted solution after 7 days\u003c\/p\u003e\n\u003ch2\u003eResearch References\u003c\/h2\u003e\n\u003cp\u003eThe following peer-reviewed studies and publications are provided for informational and scientific reference purposes only. They do not constitute medical claims or endorsements of this product for any therapeutic use.\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eSS31 Design and Mitochondrial Targeting Mechanism\u003c\/strong\u003e\u003cbr\u003eSzeto HH. (2006). \u003cem\u003eCell-permeable, mitochondria-targeted, peptide antioxidants.\u003c\/em\u003e AAPS Journal, 8(2), E277–E283. \u003ca href=\"https:\/\/doi.org\/10.1007\/BF02854898\"\u003ehttps:\/\/doi.org\/10.1007\/BF02854898\u003c\/a\u003e\u003cbr\u003eFoundational paper by the inventor of the SS peptide series, describing the design rationale for SS31 (Elamipretide) as a cell-permeable, mitochondria-targeted antioxidant tetrapeptide. Establishes the cardiolipin-binding mechanism and selective accumulation in the inner mitochondrial membrane.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSS31 and Cardiolipin Interaction: Preserving Mitochondrial Cristae\u003c\/strong\u003e\u003cbr\u003eBirk AV, et al. (2013). \u003cem\u003eThe mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin.\u003c\/em\u003e Journal of the American Society of Nephrology, 24(8), 1250–1261. \u003ca href=\"https:\/\/doi.org\/10.1681\/ASN.2012121216\"\u003ehttps:\/\/doi.org\/10.1681\/ASN.2012121216\u003c\/a\u003e\u003cbr\u003eDemonstrates that SS31 binds directly to cardiolipin on the inner mitochondrial membrane, stabilising cristae architecture, restoring electron transport chain efficiency, and improving ATP synthesis in ischaemic renal tissue — a key mechanistic study for mitochondrial bioenergetics research.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSS31 in Cardiac Ischaemia-Reperfusion Injury Models\u003c\/strong\u003e\u003cbr\u003eCho J, et al. (2007). \u003cem\u003ePotent mitochondria-targeted peptides reduce myocardial infarction in rats.\u003c\/em\u003e Coronary Artery Disease, 18(3), 215–220. \u003ca href=\"https:\/\/doi.org\/10.1097\/MCA.0b013e3280d609fe\"\u003ehttps:\/\/doi.org\/10.1097\/MCA.0b013e3280d609fe\u003c\/a\u003e\u003cbr\u003eDemonstrates significant reduction in myocardial infarct size following SS31 administration in rat ischaemia-reperfusion models, establishing its cardioprotective profile and supporting research into mitochondrial ROS scavenging during oxidative injury.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSS31 and Skeletal Muscle Mitochondrial Function in Ageing\u003c\/strong\u003e\u003cbr\u003eSiegel MP, et al. (2013). \u003cem\u003eMitochondrial-targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice.\u003c\/em\u003e Aging Cell, 12(5), 763–771. \u003ca href=\"https:\/\/doi.org\/10.1111\/acel.12102\"\u003ehttps:\/\/doi.org\/10.1111\/acel.12102\u003c\/a\u003e\u003cbr\u003eShows that acute SS31 treatment rapidly restores mitochondrial membrane potential, increases ATP production, and improves in vivo skeletal muscle contractile function in aged mice — providing key data for research into age-related mitochondrial decline and sarcopenia models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElamipretide (SS31) Clinical Translation: Heart Failure\u003c\/strong\u003e\u003cbr\u003eGibson CM, et al. (2016). \u003cem\u003eEMBRACE STEMI study: a Phase 2a trial to evaluate the safety, tolerability, and efficacy of intravenous MTP-131 on reperfusion injury in patients with ST-segment elevation myocardial infarction.\u003c\/em\u003e European Heart Journal, 37(16), 1296–1303. \u003ca href=\"https:\/\/doi.org\/10.1093\/eurheartj\/ehv597\"\u003ehttps:\/\/doi.org\/10.1093\/eurheartj\/ehv597\u003c\/a\u003e\u003cbr\u003ePhase 2a clinical trial evaluating the safety and tolerability of intravenous elamipretide (SS31\/MTP-131) in STEMI patients, providing translational context for preclinical SS31 research and establishing the compound’s clinical pharmacokinetic and safety profile.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003eAll references are cited for scientific context only. This product is supplied strictly for in vitro laboratory research. It is not approved for human or veterinary use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mutant Peptides","offers":[{"title":"Default Title","offer_id":53248680132951,"sku":"2S10","price":26.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1007\/3581\/1927\/files\/ss31-10mg_627cd29c-9356-4b11-89e7-afaeea5f0afb.png?v=1779544505"},{"product_id":"glutathione-1500mg","title":"Glutathione 1500mg","description":"\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1007\/3581\/1927\/files\/GLUTATHIONE_1500_GLOSS.png?v=1779040068\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cp\u003eGlutathione 1500mg Peptide Powder harnesses the power of bioactive peptide technology to deliver maximum antioxidant impact. Each serving provides a concentrated dose of reduced L-glutathione in powder form for flexible dosing and rapid absorption. This advanced formulation supports cellular regeneration, immune resilience, and systemic detoxification. Ideal for athletes, biohackers, and wellness enthusiasts seeking clinical-grade antioxidant support. Mix with water or your preferred beverage for seamless integration into your daily protocol.\u003c\/p\u003e\n\u003cp\u003eGlutathione is a tripeptide composed of three amino acids: glutamic acid, cysteine, and glycine. The reduced form (L-glutathione) features a free thiol group (-SH) on the cysteine residue, which is the active site responsible for its potent antioxidant properties. This molecular structure enables glutathione to donate electrons and neutralise free radicals, protecting cellular integrity. The peptide bond configuration ensures stability and bioavailability in our premium formulation, making it highly effective for systemic antioxidant support and detoxification pathways.\u003c\/p\u003e\n\u003cp\u003eStorage Before Reconstitution: Keep the powder in its original sealed container in a cool, dry place away from direct sunlight and moisture. Store at room temperature (15–25°C). Avoid exposure to heat and humidity, which can degrade the reduced glutathione. Properly sealed, the powder maintains potency for 24 months from the date of manufacture. Storage After Reconstitution: Once mixed with water or liquid, consume immediately for maximum efficacy. If preparation is necessary in advance, store the reconstituted solution in an airtight glass container in the refrigerator at 2–8°C and use within 24 hours. Oxidation may occur over time, reducing antioxidant potency. Do not freeze reconstituted solutions.\u003c\/p\u003e\n\u003ch2\u003eResearch References\u003c\/h2\u003e\n\u003cp\u003eThe following peer-reviewed studies and publications are provided for informational and scientific reference purposes only. They do not constitute medical claims or endorsements of this product for any therapeutic use.\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eGlutathione: Biochemistry and Antioxidant Function\u003c\/strong\u003e\u003cbr\u003eMeister A \u0026amp; Anderson ME. (1983). \u003cem\u003eGlutathione.\u003c\/em\u003e Annual Review of Biochemistry, 52, 711–760. \u003ca href=\"https:\/\/doi.org\/10.1146\/annurev.bi.52.070183.003431\"\u003ehttps:\/\/doi.org\/10.1146\/annurev.bi.52.070183.003431\u003c\/a\u003e\u003cbr\u003eThe foundational reference on glutathione biochemistry, detailing the tripeptide’s synthesis, the γ-glutamyl cycle, thiol redox chemistry, and its central role in cellular antioxidant defence and detoxification — essential background for any glutathione research programme.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGlutathione and Oxidative Stress in Disease Models\u003c\/strong\u003e\u003cbr\u003eBallatori N, et al. (2009). \u003cem\u003eGlutathione dysregulation and the etiology and progression of human diseases.\u003c\/em\u003e Biological Chemistry, 390(3), 191–214. \u003ca href=\"https:\/\/doi.org\/10.1515\/BC.2009.033\"\u003ehttps:\/\/doi.org\/10.1515\/BC.2009.033\u003c\/a\u003e\u003cbr\u003eReviews the relationship between glutathione depletion and the pathogenesis of oxidative stress-related conditions, covering hepatic, neurological, and immune dysfunction models and establishing glutathione homeostasis as a key research target.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReduced Glutathione and Immune Function\u003c\/strong\u003e\u003cbr\u003eHamilos DL \u0026amp; Wedner HJ. (1985). \u003cem\u003eThe role of glutathione in lymphocyte activation.\u003c\/em\u003e Journal of Immunology, 135(4), 2740–2747. PMID: 4031462\u003cbr\u003eDemonstrates that intracellular glutathione levels modulate lymphocyte proliferation and immune activation in vitro, providing mechanistic context for research into glutathione’s role in immune cell function and redox signalling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOral Glutathione Bioavailability and Systemic Absorption\u003c\/strong\u003e\u003cbr\u003eRichie JP Jr, et al. (2015). \u003cem\u003eRandomized controlled trial of oral glutathione supplementation on body stores of glutathione.\u003c\/em\u003e European Journal of Nutrition, 54(2), 251–263. \u003ca href=\"https:\/\/doi.org\/10.1007\/s00394-014-0706-z\"\u003ehttps:\/\/doi.org\/10.1007\/s00394-014-0706-z\u003c\/a\u003e\u003cbr\u003eRandomised controlled trial demonstrating that oral reduced glutathione supplementation significantly increases glutathione levels in blood, erythrocytes, and buccal cells over 6 months, providing key pharmacokinetic data for oral delivery research.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGlutathione in Hepatic Detoxification and Phase II Metabolism\u003c\/strong\u003e\u003cbr\u003eHayes JD, Flanagan JU \u0026amp; Jowsey IR. (2005). \u003cem\u003eGlutathione transferases.\u003c\/em\u003e Annual Review of Pharmacology and Toxicology, 45, 51–88. \u003ca href=\"https:\/\/doi.org\/10.1146\/annurev.pharmtox.45.120403.095857\"\u003ehttps:\/\/doi.org\/10.1146\/annurev.pharmtox.45.120403.095857\u003c\/a\u003e\u003cbr\u003eComprehensive review of glutathione S-transferase enzymes and their role in Phase II hepatic detoxification, electrophile conjugation, and xenobiotic metabolism — directly relevant to research into glutathione’s systemic detoxification mechanisms.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003eAll references are cited for scientific context only. This product is intended for research and wellness use. It is not approved as a medicinal product and does not constitute medical advice.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mutant Peptides","offers":[{"title":"Default Title","offer_id":53248694583639,"sku":"GTT1500","price":32.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1007\/3581\/1927\/files\/GLUTATHIONE_1500_GLOSS.png?v=1779040069"},{"product_id":"5-amino-1mq-50mg","title":"5-Amino-1MQ 50mg","description":"\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1007\/3581\/1927\/files\/50AMINO1MQG.png?v=1779991361\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cp\u003e5-Amino-1MQ 50mg is a synthetic small-molecule compound designed for research and laboratory use. This high-purity formulation delivers 50 milligrams of 5-Amino-1-methylquinolinium, a selective inhibitor of nicotinamide N-methyltransferase (NNMT), suitable for scientific investigation and experimental applications. Each vial is manufactured to exacting standards to ensure consistency and reliability in research settings. Ideal for qualified researchers and institutions exploring metabolic regulation, NAD+ pathway modulation, and related biochemical studies. Store in a cool, dry place away from direct light. For research purposes only.\u003c\/p\u003e\n\u003cp\u003eSpecifications: Active Ingredient: 5-Amino-1-methylquinolinium (5-Amino-1MQ) Concentration: 50mg per vial Purity: Research-grade Format: Lyophilized powder Storage: Cool, dry environment, 2–8°C (refrigerated) Shelf Life: Refer to batch documentation for expiration details Intended Use: Laboratory and research applications only Quality Standard: Manufactured to pharmaceutical-grade consistency protocols Suitable for qualified researchers, academic institutions, and licensed laboratories conducting metabolic and NAD+ pathway research.\u003c\/p\u003e\n\u003cp\u003eMolecular Formula: C₁₀H₁₁N₂⁺ (as cation) Molecular Weight: 159.21 g\/mol (free base) CAS Number: 1220-83-3 Mechanism: Selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in the methylation of nicotinamide and regulation of NAD+ precursor availability and cellular energy metabolism Sequence Classification: Small-molecule quaternary ammonium compound Purity Analysis: ≥98% by HPLC This molecular data supports advanced research into NNMT inhibition, NAD+ biosynthesis pathways, adipogenesis, and metabolic homeostasis studies.\u003c\/p\u003e\n\u003cp\u003eStorage Before Reconstitution: Store the sealed vial at 2–8°C (refrigerated) or at room temperature (15–25°C) in a cool, dry place away from direct sunlight and heat sources. Keep in original packaging to protect from light exposure. Unopened vials maintain stability for the duration specified in batch documentation when stored under these conditions. Storage After Reconstitution: Once reconstituted with sterile water or appropriate diluent, store the solution at 2–8°C (refrigerated). Reconstituted solution should be used within the timeframe indicated in your batch documentation. Avoid repeated freeze-thaw cycles, which may compromise compound integrity. Keep the vial upright and away from direct light during storage. General Handling: Maintain sterile technique during reconstitution. Do not expose to extreme temperatures or prolonged room temperature conditions after mixing. For research use only. Not intended for human or veterinary use.\u003c\/p\u003e\n\u003ch2\u003eResearch References\u003c\/h2\u003e\n\u003cp\u003eThe following peer-reviewed studies and publications are provided for informational and scientific reference purposes only. They do not constitute medical claims or endorsements of this product for any therapeutic use.\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eNNMT Inhibition and Adipogenesis\u003c\/strong\u003e\u003cbr\u003eKraus D, et al. (2014). \u003cem\u003eNicotinamide N-methyltransferase knockdown protects against diet-induced obesity.\u003c\/em\u003e Nature, 508(7495), 258–262. \u003ca href=\"https:\/\/doi.org\/10.1038\/nature13198\"\u003ehttps:\/\/doi.org\/10.1038\/nature13198\u003c\/a\u003e\u003cbr\u003eDemonstrates that NNMT activity regulates adipogenesis and energy expenditure in murine models, establishing NNMT as a key metabolic enzyme target.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e5-Amino-1MQ as a Selective NNMT Inhibitor\u003c\/strong\u003e\u003cbr\u003eNeelakantan H, et al. (2018). \u003cem\u003eSelective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice.\u003c\/em\u003e Biochemical Pharmacology, 147, 141–152. \u003ca href=\"https:\/\/doi.org\/10.1016\/j.bcp.2017.11.007\"\u003ehttps:\/\/doi.org\/10.1016\/j.bcp.2017.11.007\u003c\/a\u003e\u003cbr\u003eIdentifies 5-Amino-1MQ as a potent, cell-permeable NNMT inhibitor and evaluates its effects on adipocyte differentiation and metabolic markers in vitro and in vivo.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNAD+ Precursor Availability and Cellular Metabolism\u003c\/strong\u003e\u003cbr\u003eCantó C, et al. (2015). \u003cem\u003eNAD+ metabolism and its roles in cellular processes during ageing.\u003c\/em\u003e Nature Reviews Molecular Cell Biology, 16(7), 397–408. \u003ca href=\"https:\/\/doi.org\/10.1038\/nrm4025\"\u003ehttps:\/\/doi.org\/10.1038\/nrm4025\u003c\/a\u003e\u003cbr\u003eReviews the role of NAD+ biosynthesis pathways — including the nicotinamide salvage pathway modulated by NNMT — in cellular energy homeostasis and ageing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNNMT Expression in Metabolic Disease\u003c\/strong\u003e\u003cbr\u003ePissios P, et al. (2013). \u003cem\u003eNicotinamide N-methyltransferase is regulated by fasting and liver X receptors.\u003c\/em\u003e Biochemical and Biophysical Research Communications, 430(2), 614–619. \u003ca href=\"https:\/\/doi.org\/10.1016\/j.bbrc.2012.11.095\"\u003ehttps:\/\/doi.org\/10.1016\/j.bbrc.2012.11.095\u003c\/a\u003e\u003cbr\u003eExamines NNMT regulation in hepatic tissue and its relationship to fasting states and lipid metabolism, providing mechanistic context for NNMT inhibitor research.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSmall-Molecule NNMT Inhibitors: Structure–Activity Relationships\u003c\/strong\u003e\u003cbr\u003eCampagna R, et al. (2021). \u003cem\u003eNicotinamide N-methyltransferase inhibitors: A patent review.\u003c\/em\u003e Expert Opinion on Therapeutic Patents, 31(5), 401–414. \u003ca href=\"https:\/\/doi.org\/10.1080\/13543776.2021.1866571\"\u003ehttps:\/\/doi.org\/10.1080\/13543776.2021.1866571\u003c\/a\u003e\u003cbr\u003eComprehensive review of NNMT inhibitor development including quinolinium-based compounds such as 5-Amino-1MQ, covering structure–activity relationships and research applications.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003eAll references are cited for scientific context only. This product is supplied strictly for in vitro laboratory research. It is not approved for human or veterinary use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Mutant Peptides","offers":[{"title":"Default Title","offer_id":53582590214487,"sku":"50AM","price":59.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1007\/3581\/1927\/files\/50AMINO1MQG.png?v=1779991361"}],"url":"https:\/\/www.mutantpeptides.com\/collections\/longevity-anti-ageing.oembed","provider":"Mutant Peptides Ltd","version":"1.0","type":"link"}